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Essays Biochem. (2008) 45, (223–236) (Printed in Great Britain)
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| Systems biology model databases and resources |
| Carel van Gend* and Jacky L. Snoep*†1 |
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| *Department of Biochemistry, University of Stellenbosch, Private Bag X1, Matieland 7602, South Africa, and †Manchester Centre for Integrative Systems Biology, Manchester Interdisciplinary Biocentre, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K.
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1To whom correspondence should be addressed (email jls@sun.ac.za).
Abstract
Systems biology aims at a quantitative understanding of systemic behaviour as a function of its components and their interactions. In systems biology studies computer models play an important role: (i) to integrate the components’ behaviour and (ii) to analyse experimental data sets. With the growing number of kinetic models that are being constructed for parts of biological systems, it has become important to store these models and make them available in a standard form, such that these models can be combined, eventually leading to a model of a complete system. In the present chapter we describe database initiatives that contain kinetic models for biological systems, together with a number of other systems biology resources related to kinetic modelling.
© The Authors; Journal compilation © 2008 Biochemical Society
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