Essays in Biochemistry
We are delighted to announce that in the recent Thomson Reuters 2013 Journal Citation Reports, Essays in Biochemistry received an increased Impact Factor of 4.390 reaffirming its status as an important educational resource.*
* 2013 Journal Citation Reports (Thomson Reuters, 2014)
The Essays in Biochemistry series provides undergraduates and first year postgraduates with a single source of information on the latest research in rapidly moving areas of biochemistry and molecular biology. Each chapter is written by an expert on the area of research and is a self-contained summary of the state-of-the-art of that topic.
Series Editor: Nigel Hooper (Manchester)
Edited by: Sarah Perrett, Beijing, China
Amyloid deposits, formed from misfolded and aggregated proteins, are characteristic of a number of human diseases, including Alzheimer's, Parkinson's, amyotrophic lateral sclerosis, Huntington's and the prion diseases. Although genes play a role, some more than others, in each of these diseases, age is also considered a risk factor. The manifestation of these diseases indicates a breakdown in the cellular quality control mechanisms that ensure proteins achieve and maintain their correctly folded conformations. Understanding the pathological mechanisms of these diseases and the cell's protective mechanisms is paramount for an aging world population. The present volume of Essays in Biochemistry provides an overview of topics including chemico-physico properties of amyloid determinants, the steps in protein quality control, the pathogenesis of amyloid diseases, and prion propagation in yeast. In addition, amyloid aggregates are also found in functional roles across a range of organisms. This volume therefore also delves into how bacteria, fungi and mammalian cells can utilize protein misfolding to provide biological function, which is important for understanding further the pathological mechanisms of amyloid diseases.
- Membrane nanodomains
- Edited by Ingela Parmryd
- Autumn 2014
- Plant hormone signalling
- Edited by Tom Guilfoyle and Gretchen Hagen
- Spring 2015
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Editorial Advisory Panel
If you have an idea for a volume of Essays in Biochemistry, please contact Nigel Hooper